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110 Science Pick-Up Lines That Will Make Your Crush Smile

Women are attracted to intelligent men, no question about it. However, they are even more drawn to those who can make them laugh.

What they truly desire is a companion who knows how to lighten the mood during a first date, ensuring both parties feel at ease.

A man who possesses this skill will engage a woman with amusing anecdotes or flirty quips.

But I’m thinking of incorporating some science-inspired pick-up lines that are sure to bring a smile to any woman’s face.

Below is a collection of lines you can utilize on your initial meeting or to inject some fun back into an ongoing relationship, so keep reading!

young couple on date

1. Hey there, I can sense a connection between us, and it’s stronger than gravitational pull!

2. You’re hotter than a Bunsen burner cranked to maximum!

3. Are you part of the periodic table? Because you are SODIUM fine!

4. Can I be your enzyme? Because my active site is yearning for a reaction.

5. Hey you, fancy forming a zygote with me?

6. I bet you’re like calcium bicarbonate—once I get you wet, the result will be explosive!

7. I must be a diamond now because you just gave me a perfect 10 in hardness.

8. We have amazing chemistry, so let’s explore some biology!

9. Ever wonder why men are considered sexier than women? Because you can’t spell sexy without the letters xy.

10. You must be a fossil because I’d love to take you out on a date.

couple looking at each other

11. You’re like an exothermic reaction, you spread your warmth everywhere!

12. You resemble telophase, as I admire your beautiful cleavage.

13. You must be exothermic because you’re definitely giving off heat.

14. My top element on the periodic table is uranium because I’m crazy about U.

15. We complement each other perfectly like hydrogen and oxygen.

16. Care for some radiometric dating? I have a rock for you!

17. I’m positive and you’re negative; together we could create a compound.

18. I am a chemist. Want to mingle and observe the reaction?

19. Are you composed of copper and tellurium? Because you definitely look CU-TE!

20. Want to share some electrons? Maybe we could establish a stable relationship.

couple laughing in cafe

21. You’re so attractive, you must be responsible for global warming!

22. Together, you and I combine to create uranium iodide.

23. If you were the study of anatomy, I’d be the study of physiology because they are always interconnected!

24. I’m trying to figure out, after years of therapy, if I might be allergic to sex.

25. If I were an endoplasmic reticulum, how would you want me: smooth or rough?

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26. You take the role of the battery, I’ll be the aluminum foil, and together we’ll illuminate the world.

27. Are you as fond of aerobic respiration as I am?

28. Baby, I’m about to break you like how a large non-polar substance disrupts a phospholipid bilayer!

29. How about you palmitoylate my protein, so I can push it into your lipid raft?

30. My affection for you is like the cosmos… infinite!

couple kissing on picnic

31. You know, math is a lot like intimacy? First, you have to remove your clothes, add yourself to the bed, spread your legs, and then there’s a 50% chance you’ll multiply.

32. I’d like to be the photon to your electron and elevate you to an excited energy level.

33. If I were able to construct my own periodic table, you would take the top position!

34. …

You must embody a cell, as my DNA resides entirely within you.35. I am like a twig… and you’re a twig too… let’s rub against each other to ignite a flame.

36. Darling, if you were oceanic crust and I became a continent, I’d let you subduct, and together we’d create hot, molten magma.

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37. I don’t need neurons to arouse your sensory pathways.

38. Are you a researcher? Because I’ve got strong feelings for you.

39. I wish to adhere to you like glue-cose.

40. Hey gorgeous, want to create a synapse with me and share neurotransmitters?

happy man kissing a girl

41. My hypothalamus must be releasing serotonin because baby, I desire you!

42. How about we head to my pad and establish a covalent bond?

43. It’s common knowledge that it’s not the vector size that counts, but how the force is applied.

44. According to the second law of thermodynamics, you’re meant to share your heat with me.

45. Hey, are you an alpha carbon? Because you seem vulnerable to a backside attack!

46. Want to slide your alpha helix into my beta barrel?

47. We connect like the sticky ends of recombinant DNA.

48. I want to work on your leucine zipper using my zinc fingers.

49. I’ll play with your vesicles while you fondle my Golgi body.

50. Are you a blend of beryllium and barium? Because you’re absolutely Ba-Be.

51. You and I would spark a more vigorous reaction than potassium and water.

52. Are you comprised of fluorine, iodine, and neon? Because you are F-I-Ne.

Are you eager for more scientific pickup lines? Continue reading!

two sassy scientist posing

53. Hey darling, will an extra drink speed up this reaction?

54. Do you enjoy science? Because I’ve got my ion you!

55. What are your thoughts on collaborative experiments?

56. Does your skin feel scorched? Because it appears you must have descended from heaven, and re-entry might have caused some issues.

57. You must resemble a fossil collection because I find you attractive.

58. We share amazing chemistry, let’s explore some biology together as well.

59. Your attire looks stunning on you but would look even better falling gently to the ground at 9.8 m/s.

60. Why not come to my room so I can illustrate the rapid growth of my natural log?

61. Blood is red; cyanosis is blue. I experience tachycardia when I think of you.

62. You must originate from the cosmos since your form is divine.

63. Upon seeing you, I feel as if I’m approaching my melting point.

couple looking at each other in eyes

64. You are more vibrant than molten lava.

65. Your angles can’t be more than 90 degrees; you’re simply too acute.

66. Are you made with beryllium, gold, and titanium? Because you are Be-Au-Ti-Ful.

67. You must have swallowed a magnet since I’m incredibly attracted to you right now.

68. To me, you’re like hydrogen because you hold the number one spot in my heart.

69. Fancy testing the spring constant of my mattress?

70. You are sweeter than fructose itself.

71. Would you like to join me in demonstrating that the Big Bang is more than just a hypothesis?

72. I’m into physics, but I assure you I’ll never be boring in the bedroom.

73. Even the Kelvin scale can’t possibly gauge how hot I believe you are.

**74.** If I were a virus, my goal would be to spread love to you. **75.** You appear more delightful than 3.14. **76.** If I were an enzyme, I’d transform into a DNA helicase just to open up your genes. **77.** You are the photon to my photosystem: you energize my electron until I arrive at my reaction center. **78.** If you were a chemical element, you would definitely be francium, for you possess the utmost allure. **79.** How about we intertwine within my beta-pleated sheets and explore my alpha-helix? **80.** Darling, if you allowed me to deliver my H+ ions into your intermembrane space, a significant conformational change in my f1 complex would be triggered. **81.** If the universe were within my programming power, I’d place you and I in adjacent memory blocks. **82.** Does your body have a mechanism for generating energy by converting water into electricity? Wow. **83.** Hey sweetie, how about steering my Pillar of Autumn? **84.** Sweetheart, let’s calculate the amplitude of our physical wave. **85.** Baby, are you composed of jet fuel? Because you are melting me away. **86.** How about we follow the change of base law, with you as the base and I as the exponent? **87.** Darling, we share some undeniable chemistry together… during the next period. **88.** Even if there was no gravity on this planet, I would still find myself falling for you. **89.** Let’s delve into our coefficient of friction. **90.** You must be on the Mohs scale, as you make me tougher than a diamond. **91.** You are the HCl to my NaOH; let’s create something beautiful and form an ocean together. **92.** Honey, you must be a neuron because you possess impressive action potential. **93.** My attraction to you is so intense that scientists would need to discover a fifth fundamental force. **94.** You appear to be moving at light speed, as time seems to halt whenever I gaze at you. **95.** Explaining my affection for you would be akin to trying to articulate the concept of dividing by zero; it simply cannot be defined. **96.** You must be a right angle because you look just right to me. **97.** There’s so much energy flowing between us; it’s as if we are a galvanic cell. **98.** I would love to venture into outer space to embark on an adventure exploring Uranus. **99.** You must be mitochondria, for you are the powerhouse of my heart. **100.** Let’s partner up in the lab; I’m eager to conduct some experiments with you, especially in biology. **101.** You must be transitioning from solid to gas because you strike me as sublime. **102.** I’m a chemist. Care to allow me to conduct experiments with you? **103.** Are you certain we haven’t shared a class before? I could swear we had chemistry together. **104.** Do you desire for me to occupy your orbital? **105.** I believe you and I could maintain balance like Uranium 235 and Uranium 238. **106.** Rather than merely observing, I wish I could be a little more hands-on with you. **107.** Your refractive index must be over 2.42, as your beauty surpasses any diamond’s brilliance. **108.** Would you like me to crush my pestle into your mortar? **109.** I have a feeling that we are meant to be together as we argon. **110.** I think you’re hotter than sulfur hydroxide mixed with ethyl acetate.

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